Publications

2023

Yicheng Luo, Peng He, Nivedita Kanrar, Katalin Fejes Toth, Alexei A. Aravin. Maternally inherited siRNAs initiate piRNA cluster formation (2023) Mol Cell. 83(21):3835-3851.e7. doi: 10.1016/j.molcel.2023.09.033. 

Peiwei Chen and Alexei A. Aravin. Genetic control of a sex-specific piRNA program. (2023). Current Biology. 33(9):1825-1835.e3. doi: 10.1016/j.cub.2023.03.057. 

Baira Godneeva, Maria Ninova, Katalin Fejes Tóth, Alexei A. Aravin. SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes (2023). Elife. 12:RP89493. doi: 10.7554/eLife.89493. 

Maria Ninova, Hannah Holmes, Brett Lomenick, Katalin Fejes Tóth, Alexei A. Aravin. Pervasive SUMOylation of heterochromatin and piRNA pathway proteins (2023). Cell Genomics  DOI:https://doi.org/10.1016/j.xgen.2023.100329 

Godneeva B, Fejes Tóth K, Quan B, Chou TF, Aravin AA. Impact of Germline Depletion of Bonus on Chromatin State in Drosophila Ovaries. (2023) Cells. 12(22):2629. doi: 10.3390/cells12222629. 

Lisitskaya L, Kropocheva E, Agapov A, Prostova M, Panteleev V, Yudin D, Ryazansky S, Kuzmenko A, Aravin AA, Esyunina D, Kulbachinskiy A. Bacterial Argonaute nucleases reveal different modes of DNA targeting in vitro and in vivo. (2023) Nucleic Acids Res. 51(10):5106-5124. doi: 10.1093/nar/gkad290. 

Olina A, Agapov A, Yudin D, Sutormin D, Galivondzhyan A, Kuzmenko A, Severinov K,   Aravin AA, Kulbachinskiy A. Bacterial Argonaute Proteins Aid Cell Division in the Presence of Topoisomerase Inhibitors in Escherichia coli. (2023). Microbiol Spectr. 11(3):e0414622. doi: 10.1128/spectrum.04146-22. 

Daria Esyunina, Anastasiia Okhtienko, Anna Olina, Vladimir Panteleev, Maria Prostova, Alexei A. Aravin, Andrey Kulbachinskiy. Specific targeting of plasmids with Argonaute enables genome editing. (2023). Nucleic Acid Research. 51(8):4086-4099. doi: 10.1093/nar/gkad191. 

Zsolt G. Venkei, Ildar Gainetdinov, Margaret R. Starostik, Charlotte P. Choi, Peiwei Chen, Chiraag Balsara, Troy W. Whitfield, George W. Bell, Suhua Feng, Steven E. Jacobsen, Alexei A. Aravin, John K. Kim, Philip D. Zamore, Yukiko M. Yamashita. A maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila. (2023) Nat Cell Biol. 25(10):1495-1505. doi: 10.1038/s41556-023-01227-4.

2022

Lisitskaya L, Shin Y, Agapov A, Olina A, Kropocheva E, Ryazansky S, Aravin AA, Esyunina D, Murakami KS, Kulbachinskiy A. Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity. (2022). Nat Commun. 13(1):4624. doi: 10.1038/s41467-022-32079-5

2021

Chen P, Luo Y, Aravin AA. RDC complex executes a dynamic piRNA program during Drosophila spermatogenesis to safeguard male fertility. (2021) PLoS Genet. 17(9):e1009591. doi: 10.1371/journal.pgen.1009591. 

Huang X, Hu H, Webster A, Zou F, Du J, Patel DJ, Sachidanandam R, Toth KF, Aravin AA, Li S. Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex. (2021) Nat Commun. 12(1):4061. doi: 10.1038/s41467-021-24351-x. 

Chen P, Kotov AA, Godneeva BK, Bazylev SS, Olenina LV, Aravin AA. piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline. (2021) Genes Dev. 35(11-12):914-935. doi: 10.1101/gad.345041.120. PMID: 33985970; 

Kropocheva E, Kuzmenko A, Aravin AA, Esyunina D, Kulbachinskiy A. A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis. (2021) Nucleic Acids Res. 49(7):4054-4065. doi: 10.1093/nar/gkab182.

2020

Kuzmenko A, Oguienko A, Esyunina D, Yudin D, Petrova M, Kudinova A, Maslova O, Ninova M, Ryazansky S, Leach D, Aravin AA, Kulbachinskiy A. DNA targeting and interference by a bacterial Argonaute nuclease (2020) Nature 587(7835):632-637. doi: 10.1038/s41586-020-2605-1.

Ninova M, Chen YA, Godneeva B, Rogers AK, Luo Y, Fejes Tóth K, Aravin AA. Su(var)2-10 and the SUMO Pathway Link piRNA-Guided Target Recognition to Chromatin Silencing (2020) Mol Cell. 77(3):556-570.e6. doi: 10.1016/j.molcel.2019.11.012. 

Ninova M, Godneeva B, Chen YA, Luo Y, Prakash SJ, Jankovics F, Erdélyi M, Aravin AA, Fejes Tóth K. The SUMO Ligase Su(var)2-10 Controls Hetero- and Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation (2020) Mol Cell. 77(3):571-585.e4. doi: 10.1016/j.molcel.2019.09.033. 

Cheng Luo, Elena Fefelova, Maria Ninova, Yung-Chia Ariel Chen, Alexei A. Aravin. Repression of interrupted and intact rDNA by the SUMO pathway in Drosophila melanogaster (2020) Elife 9:e52416. doi: 10.7554/eLife.52416. 

Olina A, Kuzmenko A, Ninova M, Aravin AA, Kulbachinskiy A, Esyunina D. Genome-wide DNA sampling by Ago nuclease from the cyanobacterium Synechococcus elongatus (2020). RNA Biol. 17(5):677-688. doi: 10.1080/15476286.2020.1724716. 

Lisitskaya L, Petushkov I, Esyunina D, Aravin A, Kulbachinskiy A.Recognition of double-stranded DNA by the Rhodobacter sphaeroides Argonaute protein. (2020) Biochem Biophys Res Commun. 533(4):1484-1489. doi: 10.1016/j.bbrc.2020.10.051.

Invited reviews and book chapters

Archive